Lee Knowles' Book on Mitochondria and Its Impact on Future Medical Science

JB: A good introduction to mitochondria.
I hope there will be an updated book in the near future, as the discoveries in mitochondrial influence on human health are evolving fast and the link between gut microbiota and mitochondria is fascinating.

United Kingdom on Dec 22, 2023

Sumanta: Very good book and very informative

India on Aug 03, 2022

Javier C Gonzalez: Muy interesante y bien escrito, por lo que se facilita su lectura, a pesar de la complejidad del tema.

Mexico on Aug 02, 2022

fly fishihg pete: Great book to get an understanding how your body produces the energy one needs to live. Is it the be all and end all to understanding all degenerative disease and the cause of ageing ? No doubt it's part of the cause but It seems to me that he kinda gave short thrift to other theories .Page 44 and 45 endocrine theory of ageing is caused by a fall in hormones but he doesn't mention HGH . His argument is why do these hormones start to fall in the first place. And seems to think that that ends the discussion..It doesn't!

The question should be why shouldn't it fall over time? Consider this HGH repairs soft tissue damage including DNA damage done by free radicals. This may well be what keeps the young as healthy as they are. Evolution and natural selection only have one concern that we live long enuff to pass our genes along and stay alive long enuff to see our offspring to adulthood . Thus there's no REASON for the glands to continue producing HGH once the time has passed for that to be accomplished. But one can stimulate the production of HGH with proper exercise and diet. For more on this subject "Natural Hormonal Enhancement"can be gotten here on...

United States on Apr 17, 2020

Benthamite: This is the best book I have read on mitochondria and pathologies, and thus I highly recommend it. For the medical nerd, like me (with the largest health website independent of industries) I find major pieces of the puzzle missing (parts that I am including in my book that is 2 years from publication). He misses the case made against sugar (Gary Taubes and Robert Lustig) and the conditions of affluence also called AGEs (advanced glycation end-products) which explain how sugar causes mitochondrial dysfunction. Fructose the reactive sugar bonds with proteins and polyunsaturated fats transported into the mitochondria. Lacking the fructose entails the harm fructose does through fructosylation.

On the plus side is his excellent ability to communicate to a health educated audience, the many, many insights he has on processes. This book is a giant step forward for those struggling with the puzzle of our health disaster have not included mitochondria dysfunction. fructosylation is the reactive chemical that has overloaded the repair processes for the mitochondria. Most researchers on the right path stop with insulin resistance and too much refined...

United States on Nov 29, 2019

Josh B.: So much good information in this book, and it's put into a format that makes a really complicated subject easier to digest. I am recommending this book to everyone I know.

Dr. Doug Wallace (considered the godfather of mitochondria research) is another great resource for all things mitos, but most of his talks on YT are geared towards clinicians.

Another brilliant doctor, Dr. Jack Kruse, has figured out the quantum biological relationship between our light environment and mitochondria. I would highly recommend him as well if this is a subject that interests you. Turns out sunlight can fix a lot of our ills (and eliminating artificial blue light exposure through your eyes and skin), and this information is withheld (or represented as a poison, which is ridiculous) from the public because they haven't figured out how to charge us for sunlight...........yet.

United States on Nov 21, 2019

Emacedo: Livro com excelente explicação de aspectos básicos do funcionamento celular envolvidos com a mitocôndria, que serve de apoio para o desenvolver as relações patológicas e nutricionais relacionadas com a tese do autor quanto a disfunção mitocondrial. Excelente livro.

Brazil on Dec 19, 2018

Doobie Pagoda: This is one of the most important books I have ever read in my life. I believe Dr. Know is correct in describing mitochondria as being the future of medicine.

The book is divided into three main parts. First, there's a description of what the mitochondria are and how they work. This portion may be a bit difficult for the average reader, but is well worthwhile in setting a foundation for the remainder of the book. I was fortunate in having recently taken an introductory course in biology at the university level, so I knew some of this stuff, but even so, Dr. Know provides additional information that wasn't covered in my course.

For instance, I had never heard before that it takes more ATP (the cellular energy chemical) to move a muscle into the relaxed position than it takes to make the muscle contract. This is why bodies get rigor mortis after death—the mitochondria in the cells are no longer producing ATP, so muscles stay contracted rather than relaxing and elongating. But far more importantly, this explains why people with poor mitochondrial function experience muscle stiffness—in arthritis, for example.

The second part describes how...

Canada on Aug 19, 2018

Rev.Miriam: Mitochondria and the Future of Medicine is a fairly complex read. It's not for a complete beginner, though the author simplifies the over-all concepts in the beginning as much as he can. I would recommend this book to health care professionals to further their already solid base of knowledge in nutrition, the Krebs Cycle and metabolic disorders such as Diabetes, Metabolic Syndrome, Obesity, etc. Lee Know knows his material and presents it as clearly and concisely as he can, which is quite good, all the while reminding the reader that discoveries are continuously being made, causing our understanding to change. But the foundational information and its current ramifications Know puts forward, is exciting, fascinating and hopeful. I give it 5 stars. It's a solid piece of excellent work.

United States on Apr 26, 2018

Jack K.: Can someone please explain why Dr. Know released this book with a new title when it contains virtually the same content as his previous "LIFE - The epic story of our mitochondria"???

It's STILL a great book, one that will change your understanding of the aging process. Dr. Know uses his knowledge of mitochondria and the mitochondrial theory of aging to elucidate the role of mitochondria in chronic disease, from cancer, heart disease, metabolic syndrom and diabetes to neurological diseases like Alzheimer's, Parkinson's, Huntington's, ALS, ADHD, anxiety and depression. He explains how understanding the role of mitochondria in chronic disease closes many of the holes left by the "Free Radical" theory of aging and suggests rational interventions that should result in healthier mitochondria and longer health span. Excellent job!

United States on Mar 10, 2018